Introduction

2,4-Dichloropyrimidine is a crucial organic compound with diverse applications across several industries. Its chemical structure and properties make it valuable in pharmaceuticals, agrochemicals, and materials science. This article will explore its structure, physical properties, production process, solubility, properties, safety, and handling considerations, providing a comprehensive overview of this compound.

Chemical Structure

The chemical structure of 2,4-dichloropyrimidine(Cas N0: 3934-20-1) consists of a pyrimidine ring with chlorine atoms attached at the 2nd and 4th positions. Its molecular formula is C4H2Cl2N2, and its molecular weight is approximately 148.98 g/mol. This structure gives it its unique reactivity and versatility in various chemical reactions.

Physical Properties

2,4-Dichloropyrimidine is a white to light yellow crystalline solid with a melting point around 76-78°C. It is sparingly soluble in water but readily dissolves in organic solvents such as acetone, ethanol, and ether. Its solubility and melting point are essential in industrial applications and synthesis processes.

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Production Process

The production of 2,4-dichloropyrimidine typically involves chlorinating pyrimidine derivatives under controlled conditions. Various methods exist for its synthesis, including chlorination of 2,4-dihydroxy pyrimidine or direct chlorination of pyrimidine itself. These processes require careful control of temperature, pressure, and reactant ratios to achieve high yields and purity.

Solubility

2,4-Dichloropyrimidine exhibits limited solubility in water, making organic solvents the preferred medium for handling and processing. Its solubility characteristics influence the choice of solvent and reaction conditions in its synthesis and applications.

Properties

Apart from its solubility and melting point, 2,4-dichloropyrimidine possesses other notable properties. It is stable under normal conditions but may decompose upon heat, light, or incompatible chemical exposure. Its reactivity allows for various chemical transformations, including substitution, addition, and condensation reactions, making it valuable in organic synthesis.

Safety and Handling

As with any chemical compound, proper safety measures must be followed when handling 2,4-dichloropyrimidine. Upon contact or inhalation, it may irritate the skin, eyes, and respiratory system, necessitating the use of protective equipment such as gloves, goggles, and a respirator. Adequate ventilation and containment measures should be in place to prevent exposure and minimize the risk of accidents.

Conclusion

In conclusion, 2,4-dichloropyrimidine is a versatile compound with significant importance in various industries. Its unique chemical structure and properties enable its use in synthesising pharmaceuticals, agrochemicals, and other organic compounds. Understanding its physical and chemical characteristics, production methods, solubility, and safety considerations is essential for its practical and responsible utilization in industrial and research applications.